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abnormalities (i.e., ventricular enlargement and volume reductions) are present in other disorders, both neurological and psychiatric. Other common signs include bizarre facial expressions, such as repeated grimacing or staring, and repeated peculiar gestures that often involve complex behavioral sequences. Such programs often play a major role in helping patients recover from their illness. Most notable were reductions in the volume of certain brain regions, especially the hippocampus, and increases in the size of the ventricles. Twin studies rely on the fact that MZ twins essentially share 100 of their genes. Within the past decade, some new, atypical antipsychotic drugs have been introduced. The Most Recent Schizophrenia Biology News. See following link for the, archived Full List of Biology of Schizophrenia News.
But community support services and transitional living arrangements were not readily available to many patients. The modal age at onset of schizophrenia is in early adulthood, usually before 25 years of age.
In addition to hallucinations and delusions, the DSM lists three other key symptoms of schizophrenia: disorganized speech, disorganized or catatonic behavior, and negative symptoms. Early treatment seems to be important in that the shorter the period between the onset of the patients symptoms and the first prescribed medication, the better the clinical outcome. Paul Greengard, Professor and Head of the Laboratory of Molecular and Cellular Neuroscience at Rockefeller University. As research findings on the biochemical aspects of schizophrenia accumulate, it increasingly appears that the illness may involve multiple neurotransmitters, with different biochemical profiles for different patients. Exposure to stress within the context of the family has been the focus of researchers in the field. Some investigators have studied the development of adopted children whose biological mothers had schizophrenia. At the same time, the associated long- and short-term side effects of antipsychotics, especially the typical antipsychotics, are of continuing concern to patients, their families, and physicians. Bleuler attempted to identify an underlying commonality among the diverse variations of what Kraepelin referred to as dementia praecox and concluded that all of the patients suffered from a breaking of associative threads, causing a disharmony among communicative and thought processes. Patients classified as having undifferentiated schizophrenia do not meet criteria for any of the previous subtypes. The same pattern was apparent for the relation between OCs and adult brain morphology, suggesting that pre- and perinatal factors contribute to brain abnormalities. Research indicated that the typical antipsychotics, such as haloperidol, decreased the symptoms of schizophrenia, especially positive symptoms, and reduced the risk of relapse.
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